Adjuvant and Antibody Production Resources: Comparisons and Alternative Technologies
USDA. NAL. Animal Welfare Information Center.
Includes guidelines and policies, a list of web sites and organizations, bibliographies, and a 1997 report from an ECVAM workshop on monoclonal antibody production.
Guidelines on Monoclonal Antibody Production (PDF | 2.2MB)
Australian Government. National Health and Medical Research Council.
The basic message contained within these guidelines is that the use of the ascites fluid method for the production of monoclonal antibodies (MAbs) is no longer acceptable.
Guidelines on Antibody Production (PDF | 2.22 MB)
Canadian Council on Animal Care.
Guidelines for the production of both polyclonal (pAb) and monoclonal antibodies (mAb) that assist investigators and research support personnel to achieve an acceptable immunological result with minimal discomfort for the animals involved.