Animal Welfare Information Center News Feed

The Animal Welfare Information Center News Feed pulls together news items related to animal health, behavior and welfare. It also provides information on new AWIC publications and changes to the AWIC Web site.

Monday, January 26, 2015 - 12:42
Institute for Laboratory Animal Research (ILAR)

Workshop April 20-21, 2015: Performance Standards in the Care and Use of Laboratory Animals
As anyone involved with care and use of research animals knows, designing and managing an effective program is a size-fits-all exercise. Applying care and use guidelines requires interpretation, professional input, sound judgment, and a team approach, all of which are importance features of performance standards. The National Research Council’s ILAR Roundtable invites you to join this free workshop where experts from around the world will discuss established performance standards and how they might be improved to conform with today’s experimental environment.

Wednesday, January 21, 2015 - 06:54
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

NTP RELEASES HANDBOOK ON SYSTEMATIC REVIEW. The NTP Office of Heath Assessment and Translation (OHAT) at the National Institute of Environmental Health Sciences has released a handbook describing standard operating procedures for implementing systematic review in OHAT evaluations. The handbook also includes OHAT’s tool for assessing study quality, or “risk of bias,” that applies a parallel approach to evaluation of risk of bias for human and non-human animal studies.

The handbook is available at Additional information about OHAT and its activities is available at

Wednesday, January 21, 2015 - 06:54
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

The National Toxicology Program (NTP) is seeking to increase awareness and familiarity within the research community with high-throughput screening efforts and associated data and tools, and to foster the training of postdoctoral fellows and new and early-stage investigators in this area. As part of this effort, NTP will provide approximately 10 travel awards to support the costs of attending and participating in a 2015 meeting relevant to this topic being organized by the Environmental Defense Fund. The meeting, “Elucidating Environmental Dimensions of Neurological Disorders and Disease: Understanding New Tools from Federal Chemical Testing Programs” will be held on June 18-19, 2015, at the University of California–Davis.

The travel awards are aimed at new and early-stage investigators considering using high-throughput screening in research to investigate the potential effects of environmental chemicals on neurological disorders and disease. Depending on the number of applications received, priority may be given to applicants who have not previously received a travel award from the National Institute of Environmental Health Sciences. The deadline for application for the travel awards is February 27.

More information about the awards is available at

Wednesday, January 21, 2015 - 06:54
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

WORKSHOP ON IN VITRO TOOLS AND MODELS FOR DRUG DISCOVERY A free workshop on “Validation and Qualification of New In Vitro Tools and Models for the Pre-clinical Drug Discovery Process” will be presented at the National Institutes of Health (NIH) on February 12. The workshop is being organized by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) in partnership with the American Institute for Medical and Biological Engineering and the National Center for Advancing Translational Sciences (NCATS).

The workshop will be held in the Lister Hill Auditorium on the NIH campus in Bethesda, Maryland. Additional information, agenda, a link to registration, and information on previous workshops in this series can be found at

Wednesday, January 14, 2015 - 10:23
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

A draft U.S. Environmental Protection Agency (EPA) document describing a “Process for Establishing and Implementing Alternative Approaches to Traditional In Vivo Acute Toxicity Studies” is now available for comment. The document describes a transparent, stepwise process for evaluating and implementing alternative methods of testing for acute oral, dermal, and inhalation toxicity, along with skin and eye irritation and skin sensitization. In addition, there is a discussion of the three major phases of the process and the implications for reporting information under the Federal Insecticide, Fungicide, and Rodenticide Act.

The draft document is on the EPA website at Please submit comments on the document to Christopher Schlosser at Comments will be accepted until March 10.

Wednesday, January 14, 2015 - 10:19
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

ICCVAM is presenting a webinar on “Reverse Toxicokinetics: Using In Vitro Data to Estimate Exposures that Could Be Associated with Adverse Effects In Vivo” on January 27. The webinar will focus on the development and application of reverse toxicokinetic models for extrapolation of high-throughput screening data to in vivo dosimetry. John Wambaugh, Ph.D., Physical Scientist at the EPA’s National Center for Computational Toxicology (NCCT), will provide an overview of the development of reverse toxicokinetic models. Barbara Wetmore, Ph.D., Senior Research Investigator at the Hamner Institutes for Health Sciences, will discuss the consideration of population variability and sensitive subpopulations in the use of these models. NICEATM and NCCT are hosting the webinar on behalf of ICCVAM.

Information about the webinar and a link to registration are available at Registration will be available until the webinar begins at 1:00 p.m. Eastern Standard Time.

The use of reverse toxicokinetic models to compare in vitro and in vivo estrogen receptor activity was the subject of a recent NICEATM publication in the journal Applied In Vitro Toxicology. The paper is available at

AOP Workshop Abstract Deadline, PBPK Modeling Course, USDA Training on Alternatives, ASCCT Annual Meeting
Thursday, July 24, 2014 - 08:21
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)


Scientific poster abstracts for the upcoming workshop “Adverse Outcome Pathways: From Research to Regulation” are due by close of business on Friday, July 25. Posters should address how adverse outcome pathways may be developed or used (i) to predict toxic effects in humans or ecological systems or (ii) to improve regulatory assessment of chemical toxicity. Posters that address related issues or topics may be considered as space allows. Applications for travel support by students or postdoc presenters are also due July 25.

Submit poster abstracts and applications for travel support by email to Michael Paris ( The corresponding author will be notified of an abstract’s acceptance and provided with guidelines for poster presentation by August 4. Travel support awardees will be notified by August 5. Information on abstract submission, travel support competition, and links to registration are available at

The workshop will be held September 3-5 at the William H. Natcher Conference Center at the National Institutes of Health in Bethesda, Maryland. It is open to the public free of charge with attendance limited only by the space available. The plenary sessions of the workshop will be webcast. Individuals who plan to attend in person or view the webcast should register by August 15.


The Hamner Institutes for Health Sciences is offering a one-week course on the principles of physiologically based pharmacokinetic (PBPK) modeling and the application of this technique in risk assessment, drug development, in vitro to in vivo extrapolation (IVIVE), and estimation of exposures from human biomonitoring data. The course features comprehensive lectures and extensive hands-on computer modeling practice. Students completing this course can earn up to 30 hours of American Board of Industrial Hygiene Certification Maintenance credit.

The course will be offered September 22-26 at the Hamner Institutes in Research Triangle Park, NC. More information and a link to registration are available at Registration closes September 12.


USDA’s Animal Welfare Information Center (AWIC) holds free workshops at the National Agricultural Library to help researchers explore alternatives to procedures that may cause pain or distress to their animals. Training is targeted to principal investigators, IACUC members, administrators of animal use programs, veterinarians, librarians, and other information specialists. The workshops provide an overview of relevant topics and resources, instruction on the use of existing databases and websites, and hands-on practice conducting online database searches.

Registration is open for the next workshop, which takes place Nov. 12-14, 2014. Registration is available at; workshops are limited to 20 participants.

AWIC staff members are also available to also to provide training at your institution or conduct training via webinar. Please contact AWIC at 301-504-6212 or at for more information.


The theme of the third Annual Meeting of the American Society for Cellular and Computational Toxicology is “Where Chemistry and Biology Meet: AOPs as a Framework for Advancing Toxicology.” Dr. Robert Kavlock, Deputy Assistant Administrator for Science and interim Science Advisor at the U.S. Environmental Protection Agency, will deliver a plenary lecture on adverse outcome pathways. Other invited speakers will discuss computational toxicity tools based on AOPs for liver toxicity and the National Institutes of Health (NIH) Big Data to Knowledge initiative.

The meeting will be held November 12th in the National Library of Medicine Lister Hill Auditorium on the NIH campus in Bethesda, MD. Registration is $75 and includes lunch and a reception. Abstracts for poster presentations should be submitted to ASCCT secretary Kristie Sullivan at by September 26; a small number of abstracts will be selected for oral presentations. More information is available at

Thursday, March 13, 2014 - 13:22
USDA. APHIS. Animal Care.

The U.S. Department of Agriculture’s Animal and Plant Health Inspection Service (APHIS) is continuing to move swiftly and consistently to take enforcement action in response to animal welfare violations. As part of its effort to make its actions transparent and accessible to the public, APHIS is highlighting enforcement actions taken in response to violations of the Animal Welfare Act (AWA) and Horse Protection Act (HPA).

Thursday, March 13, 2014 - 09:31
USDA. APHIS. Wildlife Services.

Taking on an adult grizzly bear or a pack of wolves is a lot to ask of a livestock protection dog, but it’s a task they willingly take to protect their herds from predation. For centuries, livestock protection dogs have helped ranchers protect livestock from coyotes, feral dogs, foxes, and mountain lions. Without them, thousands of sheep, lambs, and calves would be killed or injured each year.

Thursday, March 13, 2014 - 09:27
USDA. APHIS. Animal Care.

USDA Animal Care has revised its factsheet entitled Questions and Answers: Regulation of Dog/Cat Breeders and Dealers.

This factsheet provides information that we hope you find useful, including: 1) the types of dog/cat breeders and dealers regulated under the Animal Welfare Act; 2) the standards of care required by USDA; and 3) USDA’s role in the commercial transport of dogs/cats.